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Asymmetric Organic Synthesis with Enzymes

Asymmetric Organic Synthesis with Enzymes PDF Author: Vicente Gotor
Publisher: John Wiley & Sons
ISBN: 9783527318254
Category : Science
Languages : en
Pages : 340

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Book Description
Perfect for biochemists, synthetic and organic chemists, this book covers all important reactions, including C-C coupling reactions, oxidation reactions and many more. Divided into two parts, the first section on methodology presents new innovative methods for enzymatic catalysis optimization, including such new trends as medium engineering, directed evolution and computer-aided prediction of enantioselectivity. The second and main section deals with applications to synthesis, showing important reaction types and their applications. Only those reactions with very high selectivity are presented, allowing readers to improve their own reaction yields.

Asymmetric Organic Synthesis with Enzymes

Asymmetric Organic Synthesis with Enzymes PDF Author: Vicente Gotor
Publisher: John Wiley & Sons
ISBN: 9783527318254
Category : Science
Languages : en
Pages : 340

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Book Description
Perfect for biochemists, synthetic and organic chemists, this book covers all important reactions, including C-C coupling reactions, oxidation reactions and many more. Divided into two parts, the first section on methodology presents new innovative methods for enzymatic catalysis optimization, including such new trends as medium engineering, directed evolution and computer-aided prediction of enantioselectivity. The second and main section deals with applications to synthesis, showing important reaction types and their applications. Only those reactions with very high selectivity are presented, allowing readers to improve their own reaction yields.

Enzymes in Organic Synthesis

Enzymes in Organic Synthesis PDF Author: Ruth Porter
Publisher: John Wiley & Sons
ISBN: 0470718625
Category : Science
Languages : en
Pages : 192

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Book Description
The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.

Enzymes as Catalysts in Organic Synthesis

Enzymes as Catalysts in Organic Synthesis PDF Author: Manfred P. Schneider
Publisher: Springer Science & Business Media
ISBN: 9400946864
Category : Science
Languages : en
Pages : 422

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Book Description
Proceedings of the NATO Advanced Research Workshop, Reisensburg/Ulm, Donau, Germany, June 16-22, 1985

Enzymes in Organic Synthesis

Enzymes in Organic Synthesis PDF Author: Kevin Kun-Chin Liu
Publisher:
ISBN:
Category : Catalysts
Languages : en
Pages : 388

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Asymmetric Synthesis with Chemical and Biological Methods

Asymmetric Synthesis with Chemical and Biological Methods PDF Author: Dieter Enders
Publisher: John Wiley & Sons
ISBN: 3527610634
Category : Science
Languages : en
Pages : 470

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Book Description
Edited by two of the leading researchers in the field, this book provides a deep, interdisciplinary insight into stoichiometric and catalytic reactions in this continuously expanding area. A plethora of top German scientists with an international reputation covers various aspects, from classical organic chemistry to process development, and from the theoretical background to biological methods using enzymes. Throughout the focus is on the development of new synthetic methods in asymmetric synthesis, the synthesis of natural and bioactive compounds and the latest developments in both chemical and biological methods of catalysis, as well as the investigation of special technical and biotechnical aspects.

Enzymatic Reactions in Organic Media

Enzymatic Reactions in Organic Media PDF Author: A. Koskinen
Publisher: Springer Science & Business Media
ISBN: 9401106118
Category : Science
Languages : en
Pages : 314

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Book Description
The outlook of organic synthesis has changed many times during its tractable history. The initial focus on the synthesis of substances typical of living matter, exemplified by the first examples of organic chemistry through the synthesis of urea from inorganic substances by Liebig, was accepted as the birth of organic chemistry, and thus also of organic synthesis. Although the early developments in organic synthesis closely followed the pursuit of molecules typical in nature, towards the end of the 19th century, societal pressures placed higher demands on chemical methods appropriate for the emerging age of industrialization. This led to vast amounts of information being generated through the discovery of synthetic reactions, spectroscopic techniques and reaction mechanisms. The basic organic functional group transformations were discovered and improved during the early part of this century. Reaction mechanisms were elucidated at a growing pace, and extremely powerful spectroscopic tools, such as infrared, nuclear magnetic resonance and mass spectrometry were introduced as everyday tools for a practising organic chemist. By the 1950s, many practitioners were ready to agree that almost every molecule could be syn thesized. Some difficult stereochemical problems were exceptions; for example Woodward concluded that erythromycin was a "hopelessly complex target". This frustration led to a hectic phase of development of new and increasingly more ingenious protecting group strategies and functional group transformations, and also saw the emergence of asymmetric synthesis.

Multi-Step Enzyme Catalysis

Multi-Step Enzyme Catalysis PDF Author: Eduardo Garcia-Junceda
Publisher: John Wiley & Sons
ISBN: 3527623396
Category : Science
Languages : en
Pages : 256

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Book Description
The first comprehensive coverage of this unique and interdisciplinary field provides a complete overview, covering such topics as chemoenzymatic synthesis, microbial production of DNA building blocks, asymmetric transformations by coupled enzymes and much more. By combining enzymatic and synthetic organic steps, the use of multi-enzyme complexes and other techniques opens the door to reactions hitherto unknown, making this monograph of great interest to biochemists, organic chemists, and chemists working with/on organometallics, as well as catalytic chemists, biotechnologists, and those working in the pharmaceutical and fine chemical industries.

Organic Synthesis Using Biocatalysis

Organic Synthesis Using Biocatalysis PDF Author: Animesh Goswami
Publisher: Academic Press
ISBN: 012411542X
Category : Science
Languages : en
Pages : 438

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Book Description
Organic Synthesis Using Biocatalysis provides a concise background on the application of biocatalysis for the synthesis of organic compounds, including the important biocatalytic reactions and application of biocatalysis for the synthesis of organic compounds in pharmaceutical and non-pharmaceutical areas. The book provides recipes for carrying out various biocatalytic reactions, helping both newcomers and non-experts use these methodologies. It is written by experts in their fields, and provides both a current status and future prospects of biocatalysis in the synthesis of organic molecules. Provides a concise background of the application of biocatalysis for the synthesis of organic compounds Expert contributors present recipes for carrying out biocatalytic reactions, including subject worthy discussions on biocatalysis in organic synthesis, biocatalysis for selective organic transformation, enzymes as catalysis for organic synthesis, biocatalysis in Industry, including pharmaceuticals, and more Contains detailed, separate chapters that describe the application of biocatalysis

Quaternary Stereocenters

Quaternary Stereocenters PDF Author: Jens Christoffers
Publisher: John Wiley & Sons
ISBN: 3527606971
Category : Science
Languages : en
Pages : 359

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Book Description
Filling the gap in the literature, this book presents everything there is to know about this topic. By comprehensively covering the quaternary stereocenters found in a range of important and useful molecules in pharmaceutical and medicinal applications, as well as in thousands of natural products, the book provides the know-how chemists need to synthesize challenging molecules with numerous applications. A must for organic chemists in academia, the pharmaceutical industry and medicine. From the Contents: Important Natural Products Important Pharmaceuticals and Intermediates Aldol Reactions Michael Reactions and Conjugate Additions Cycloaddition Reactions Rearrangement Reactions Alkylation of Ketones and Imines Asymmetric Allylic Alkylation Asymmetric Cross Coupling and Heck Reactions Phase Transfer Catalysis Enzymatic Methods Radical Reactions

Enzymes in Organic Synthesis

Enzymes in Organic Synthesis PDF Author: Ciba Foundation
Publisher:
ISBN:
Category : Chemistry, Organic
Languages : en
Pages : 248

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Book Description